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Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?

  • Chromosomes will not condense

  • Chromosomes will be fragmented

  • Chromosomes will not segregate

  • Recombination of chromosome arms will occur

Answer

C.

Chromosomes will not segregate

Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.

Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.