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Write short notes on :

(a) Reductive amination

(b) Transamination.

Answer

(a) Reductive amination. In this process ammonia reacts with straight alpha-Ketoglutaric acid and forms glutamic acid as indicated below : 

(b) Transamination. This process involves the transfer of amino groups from one amino acid to the keto group of a keto acid. Glutamic acid is the main amino acid from which the transfer of NH2 group takes place and the other 17 amino acids are formed through transamination. The enzyme required for such raction is called transaminase.